201. GLP-1 Peptides vs “GLP-1 Supplements” – why the distinction matters A LOT

Episode 201 April 21, 2026 00:28:24
201. GLP-1 Peptides vs “GLP-1 Supplements” – why the distinction matters A LOT
Hungry for Love: Lose Weight After Toxic Relationships
201. GLP-1 Peptides vs “GLP-1 Supplements” – why the distinction matters A LOT

Apr 21 2026 | 00:28:24

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Show Notes

I’ve started recommending microdosing GLP-1 peptides for their regenerative and healing properties. 

And the cold, hard truth is: Peptides can do things that supplements can’t.  

Supplements have their place, but I’m sure you’ve seen a multitude of supplements claiming to “help your body produce more GLP-1 naturally.” 

For most Americans, that’s actually not helpful. 

Their metabolisms are busted after years of high stress, constant abuse, autoimmune conditions, chronic inflammation, a dysregulated nervous system, and decades of Diet Trauma trying to just “eat less and exercise more.”  

That’s why I’m only recommending GLP-1 peptides if you truly want to heal your metabolism and lose weight for life. 

I know it might feel more intimidating than a supplement, but I guarantee it’s far more effective. 

Keep listening and I’ll show you why. 

PS - I also share what supplements you should be taking while on a GLP-1 that will enhance your body’s healing journey. 

Ready to explore if peptides are the right fit for you? 

Right now I’m only offering GLP-1 guidance when you work with me in a 6-month or 12-month coaching container. Join me in a membership style group, or for private coaching, and I’ll walk with you every step of the way. 

From dosing, to lifestyle changes, to emotional eating support, to that abusive co-parent who's driving you crazy, I’ve got you covered. 

Schedule your free consultation to learn more: 

www.bodyyoucrave.com/schedule

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Episode Transcript

[00:00:02] Ready to lose 40 plus pounds without giving up happy hours, weekend brunches or date nights. Then it's time to uncover the hidden link between binge eating and toxic relationships. And finally break free from both. Welcome to the Hungry for Love podcast with Jillian Scott. Y' all ready? Let's go. [00:00:24] Hey. Hey. Welcome back. [00:00:26] All right, we are going to continue this deep dive into peptides. And today I want to talk about the difference between a GLP1 peptide versus a GLP1 supplement. Because one of the things that I've noticed and where I think supplement companies are coming into the picture is they want to be a part of this GLP1 conversation. And so they are creating these supplements that supposedly help your body create more natural GLP. [00:00:52] So your body naturally creates GLP1s when you eat. Anytime you consume food, our bodies are already creating some. The problem is that it only lasts about two to four minutes in the body. It is very short lived. I believe the idea from the supplement companies is they're like, well, we want to be relevant, we want to be part of the conversation. But my opinion and the way that I've seen it positioned is they are promoting GLP1 supplements as a replacement or as an option in lieu of peptides. But you cannot create the same results with a supplement that you can with a peptide. And so I think these supplement companies are going about it wrong. Just my personal opinion and I'm going to explain towards the end a better way of supplement companies being relevant and being a part of this conversation that I think would actually be very, very effective. Rather than trying to compete with somebody on peptides or try to shame and diminish peptides. [00:01:50] Really to look at, how could these companies and the products that they already offer support people who are using peptides? I think this needs to be a yes. And I'm going to explain a little bit more of that. But this is where the more that research that I do, the more that I'm looking at peptides and specifically microdosing GLP1s for their regenerative and healing properties. And as I look at what is going to create the best metabolic repair for people, what is going to help my clients, what is going to help me the most, it's going to be a peptide, not a supplement. [00:02:25] So you will not hear me promoting supplements above peptides. I think the order goes peptide first to repair and restore what's currently broken. And potentially with some support, like for gut health, for adrenal support, like there are some supplements that are beneficial while taking the peptides. [00:02:45] And then after that there are other supplements then that would be useful after pathways have already been repaired. [00:02:54] But supplements are only going to work if the body's systems are already naturally active and working and fairly optimal, or if they're already good, you're just trying to enhance it. It's like, it's good, but we want to take it up a level. For 90% of Americans, we're not good. We are very internally broken. So supplements have their place. But I don't think it's in competing with GLP1s, and I also don't think it's in creating more GLP1s in the body. I see it a different way. So for most Americans, it's not helpful just to add more GLP1 to the body because your metabolism is busted. After years of high stress, constant abuse, autoimmune conditions, chronic inflammation, a dysregulated nervous system, decades of diet, trauma, of trying to just eat less and exercise more, just trying to get your body to create more GLP one quote naturally isn't going to do you shit. And I'm sorry, I'm just going to be very frank and very direct. Potentially, once you have repaired and restored and healed internal systems in the body, most likely through peptides, then maybe these supplements could be effective. And because not everybody has dealt with trauma, inflammation, dysregulation, abuse, high stress. Right. Like I would say, there's maybe 10% of the population, I'm being very generous here, maybe 10% of the population could benefit from a natural GLP1 supplement that enhances your natural production of GLP. That's just what I have seen from the science, because there is a very core distinction between supplements and peptides. [00:04:34] So supplements can help your body to release a little bit more of a particular thing. But peptides actually activate the receptors in a meaningful way, releasing more versus receptor activation. That's what we're going for. If we want healing, if we want restoration, if we want to really create better systems in the body. If we want to fix what's broken, we have to heal it first. We have to fix the bridge. Otherwise, all of these extra GLP1s, number one, they're not lasting very long in your body. And number two, they have nowhere to go because your body is not able to properly use them. [00:05:13] So let me break down just a little bit more because I know this might seem kind of harsh, kind of mean, and I mean no disrespect to supplement companies. I just think they're going about this Wrong. And I'm going to give you an alternative way. If you do work with one of these supplement companies, I have another idea for you, promise. But you need to work with the peptides, not trying to come against them. So supplements, they are indirect and they are dependent on your body. [00:05:37] Most natural GLP1 boosting supplements. So think of things like fiber, barberine, chromium. They work by supporting blood sugar balance, slowing digestion, and maybe slightly stimulating your gut to release more of its own GLP1. But the effect is mild, inconsistent, and it's dependent on your gut health, insulin sensitivity versus resistance, stress levels, and past trauma. [00:06:03] So supplements can create a better environment for your body to function, but they don't override dysfunction from chronic stress, trauma, inflammation and insulin resistance. [00:06:14] And so if I look at my audience and my people in particular, we have chronic stress, we have long term trauma, which means we have inflammation in the body, most likely insulin resistance, even if it hasn't been diagnosed. And often autoimmune diseases and autoimmune conditions also not being diagnosed. So there is massive dysfunction in our bodies. And I look at my body the same way I would put my body in that same 90%. [00:06:41] I may not have some of the physical characteristics, I'm not carrying extra weight, but like I shared in last week's episode, my body still is doing some funky things. [00:06:51] And with a PCOS diagnosis at the core, that is a form of insulin resistance. And my view is that it's because of trauma. [00:06:59] So your body still has to be capable of producing and responding to GLP1s in the first place. And that's where a lot of it is going wrong. Our bridge, our metabolic pathways are broken. They're busted. They need actual support of those pathways. It's like a bridge that has a bunch of holes in it. We have to repair the bridge first. That's what peptides are going to do. So peptides are going to be direct and targeted signals. GLP1 agonists are different because they mimic the actual GLP1 hormone. They bind directly to GLP1 receptors and they create a clear, consistent signal in the body. [00:07:35] So they say, it's time to do your thing right now. So these GLP1 receptors that we have on organs, our nervous system, in our gut, in our brain, what happens is that agonist comes in and it binds to that receptor and now it triggers and activates the action. It now triggers an action. It's like, okay, now it's time to do this. It leads to appetite regulation, improved insulin response, brain Level satiety signaling, nervous system repair and regulation, true system healing and restoration. And this isn't just about your metabolism. Yes, that is a big piece of this, but so many other systems in your body, regardless of whether your body was doing that well before or not, because most of the time our bodies are not actually able to do this well on its own. And so we need the healing properties of the peptide. [00:08:28] Peptides don't hope your body gets the message. They deliver that message directly. They are activating systems in your body. You know me, I like a good analogy and I've tried to come up with some different ones. But if we look at even just like hormone replacement, right, like taking a supplement to boost your glp, one is like taking an herb to support estrogen production. [00:08:50] But taking a GLP1 peptide is like hormone replacement therapy. You're actually giving the body the signal it's missing to create more estrogen. In this example, it's not just about trying to stimulate or support more estrogen production. It's now triggering it and it's giving the missing pieces that it needs to actually produce it. So one is encouragement, one is activation. [00:09:15] So now, if you've never experienced trauma, prolonged bouts of stress or anxiety, if you have exceptional gut health and immune responses, if you have a balanced thyroid and sex hormones, you may see improvements from supplements. But again, I think that is at best 10% of US adults. Supplements can be helpful when the body needs support. But when the system is dysregulated because of high stress, inflammation, metabolic resistance, the body needs a clearer signal to feel safe enough to respond. [00:09:45] And that's where peptides come in. [00:09:48] The other thing that was also in my mind was that if supplements truly worked the way that a peptide did, it would not be sold over the counter. It would be treated like a medication. [00:09:57] Supplements don't directly act as hormones. They don't bind strongly to specific receptors. Therefore, the effects are smaller and less predictable. So less regulation because there's less impact. [00:10:09] Peptides, on the other hand, are signaling molecules just like hormones. [00:10:14] They have measurable potent physiological effects on the body. They directly activate internal systems like metabolism, nervous system, insulin regulation, inflammation, and more. There's more oversight because there's more impact. [00:10:30] So again, if we look at the release versus the receptor activation, supplements can help your body release more of it. But peptides actually activate the receptor in a meaningful way. [00:10:41] This is an important distinction. It's like, are we just releasing more? Are we actually activating what your body is supposed to do or what we want the body to be doing to begin with. Okay, so anytime you eat, your body releases GLP1. [00:10:55] The problem is that it's short lived. It's like two to four minutes long. Very, very short lived. It's nowhere near the magnitude of a peptide. It doesn't create the same body nervous system response and it doesn't heal the broken pathways. Supplements and peptides, they're playing a different game. The way I see it being positioned is supplements are trying to come in and compete with peptides. That is like a little league team trying to come in and compete with the major leagues. It's just not an even playing field. They do vastly different things. [00:11:29] I think that supplement companies are just wanting to be a part of the conversation. They want to be a part of this popularity around GLP1s and a part of the buzz. But I think they're looking at this the wrong way. So instead of competing with GLP1s, what I think they should be doing is instead showing customers and people who are already taking peptides how the supplements that they sell, that they offer will enhance peptide use. [00:11:58] So let me give you an example. If I was selling some supplements and I met somebody and they were on peptides, some type of semaglutide or tirzepatide in particular, right? They're on some type of GLP1 and I'd be like, oh, awesome, tell me about your experience. How has it been? Have you had any side effects? What improvements have you seen? Because people love to talk about what's working and what they've seen and what they've noticed. And then you could be like, oh, do you have a good probiotic or prebiotic? Because gut health is so important. When on One of these GLP1s, are you taking something regularly for that? [00:12:31] No. Oh, hey, I've got these pills, potions, drink, mix, whatever you got, right? But let's say you have a supplement that supports that. It's like, hey, this is a great addition to make the GLP1 use to make these peptides even more effective in your body and to make sure that your stomach is still processing and flushing everything through your system even better. Gut health is so important. And because a lot of times metabolic dysfunction can be due to leaky gut, we also want to be healing our gut. So I'd love to give you some of this, I'd love for you to try it or let me give you some resources on it if you're interested. I'd love to share some resources and let you take a look and See how this could support your GLP1 experience or support your weight loss or your healing journey or whatever it is that they're on. That's how I see it. Or adrenal support. A lot of times, again, because of the constant stress, constant inflammation, all of this activation, most people need some form of adrenal support, right? So if you're having this conversation and then you're like, oh, are you taking any type of adrenal support or supporting your adrenal glands? Right. And a lot of times people would probably say no. And it's like, oh, well, here's what studies have found. And you start to talk about how supporting your adrenal glands is going to benefit and enhance use of the peptides to really make it holistic, to give them an even better effectiveness, to sleep even better, to feel even better. [00:13:50] That's how I see supplement companies entering the conversation and doing better. Again, not competing with, but to go to everybody on the peptides and say, hey, I've got a thing that is going to make your experience even better. [00:14:05] And now when you're ready to come off of the peptides and you're slowly coming down off of them, you want to make sure that your body is still supported in ways now that things are healed, now these supplements are going to be even more effective. [00:14:17] That is the play. That is the play that supplement companies, I think are missing. [00:14:22] Now, again, I'm not connected with one. I know lots of people who sell them, who rep them, who promote them, and I think that's wonderful. Okay, this is not to bash on supplements, but for the type of people that I work with and for somebody like myself, we will not see results like we do on peptides by just using a supplement that is designed to help enhance your body's natural production. [00:14:47] It's not enough. We have to actually heal the pathways. [00:14:51] Back to my. My fun analogies. I still haven't quite fleshed this one out yet, so I'm gonna keep working on it, but I'll give you version one. I want you to imagine your metabolism is a bridge. And there's this big canyon between these two sides. And there are 15 planks of wood that make up this bridge, but five of yours are missing. So for every three that are on this bridge, one of those planks. Planks is missing. So you have holes in your bridge. Now, let's say you have supplements. And supplements are like little balls. And you want to just start rolling balls across. Because the idea is, if we can get these balls to the other side of the bridge, they'll be more effective and it'll help your body. But the balls never make it across because there are so many holes in your bridge, right? So even if it bounces over that first hole, it still lands in the second. [00:15:43] So the first solution is we have to repair that metabolic bridge. We have to repair your immune system, we have to repair your vagus nerve, we have to repair that gut and brain connection, we have to repair these other aspects of the body. And that's just what supplements cannot do. And so what I see is, number one, a war between peptides and supplements, which doesn't need to be happening. And number two, I see people getting, getting frustrated because they're not seeing results with a supplement. They're being promised these results and they are spending hundreds of dollars trying to create them. And they're not getting the results that they were promised. And now they feel very frustrated, very angry. And a lot of times what happens is we feel like it must be me instead of the product was not right for us. My view is that 93% of Americans are metabolically compromised. We do not have effectively working metabolisms, autoimmune systems, we are over inflammatory. There's so much dysregulation in the body, in part, I imagine, you know, for me, for myself in particular, I guarantee my bingeing and emotional eating patterns of the past also contributed to my insulin resistance and some gut issues. But I also know that trauma really impacted that as well. [00:17:02] So at the end of the day, both had an impact. It doesn't matter which thing contributed more or less. The fact is, very few people's bodies are going to respond super well to a supplement without having something like a peptide first to heal the pathways. [00:17:19] That's what I'm saying, is that peptides can come in first, do the healing maybe with some supplements for gut health or adrenal support. And then after the bridge has been healed, after the bridge has been fixed, once the metabolic pathways have been healed and restored and there's some regeneration now, supplements will actually work and be better in the system, be better in the body. That's how I see it. That is how supplement companies should be positioning and angling. That's how they become a part of the conversation. Not in competition, but in support. [00:17:53] And I believe this is really important. [00:17:55] If you are on a peptide of any kind, having adrenal support and gut support, some really good gut health, probiotics, greens, you're going to need some stuff there. And of course, adrenal support because with anybody who has been through trauma, and for most of us, we have been through so many bouts and rounds of trauma, we need additional support. [00:18:16] And when we can actually heal these metabolic pathways now, everything is functioning better. [00:18:24] And I was thinking about this the other day because my boyfriend's son, bless his heart, he is 17. So his view is that you should be able to fix anything with diet and exercise. I didn't talk to him about this, this was just relayed to me. And so my guess is his view fairly naive because he's young, he hasn't been in the world that long and exposed to too much. But his view is just eat better and exercise more. [00:18:49] And that is actually not the right solution. That cannot fix everything. In fact, a lot of times that will make things worse. Not only does that get permeated, it's like that can really be the health culture of, well, something's wrong with you. You're taking the easy way out, you're cheating. When really this is about repair. And when I think about this in the long term aspects of, let's say for most people, 12 to 24 months on a very low dose peptide is going to heal decades of metabolic dysfunction. But it's not going to be fast. I would say give it one to two years. There's going to be a weight loss phase, a weight maintenance phase, and then a coming off phase. But we want to make sure that before you come off, your body has properly healed those pathways internally for good. Let's say you give it two years, right? And I was thinking about this and I was like, all right, I'm 40 years old right now. Let's say I gave my body five years on this to heal and repair and restore. And I, I really didn't come off of them. I'm just cycling through them over the next five years. And in five years, though, my body now has healed and maybe now it's some hormone replacement therapy, if there's some menopause symptoms or challenges, or maybe within like the next 10 years, I would need something like that. But let's say I can come off of the GLP1s forever. [00:20:09] Now I have 45, 50 years of a healthy metabolism to keep going, like repaired internal systems that are forever changed. So for me even to spend five years on this, I'm like, hell yeah. Because I'm still gonna have another 45, maybe even 55 years to actually reap the benefits of it. I honestly, I don't think it's gonna take five years. In all reality, I'M just saying, like, let's go to the extreme, let's double, you know what I think it's actually gonna take. But this is the lens that I'm looking at it from is let's heal and address the things now and then, look at what our bodies need moving forward in the future. And for many women in their 40s, 50s, 60s, some form of hormone replacement therapy is probably a really, really great idea. I've not done as much research there. I'm not quite to that stage yet. However, this is where peptides and HRT can actually play really well together. And the better your body heals from GLP1 peptides, the more effective HRT will be. And so you don't have to be on such high doses for intervention and for that intervention to be effective. That's how I see it. That's how I'm looking at it. I feel like I had another thought, but I totally forgot what it was. Cause I had two thoughts coming at me. I don't know, it's totally escaped me now. [00:21:30] So that will just have to get saved for another episode. But this is where, as I look at what are options for clients, if a client comes in to work with me around coaching, then we're gonna work on emotional eating and trauma and really breaking free from diet trauma and that relationship trauma. But one of the missing pieces, I think is metabolic health. And I believe that the best way to do it, the fastest, most effective way to do that, is with GLP1 peptides. [00:21:58] I would see that as being one of the first steps. And then from there, supplements will likely be way more effective, way more useful. [00:22:06] That's my hot take. Take it or leave it. That's what I see. But that is just some like basic science as to how supplements operate versus peptides. And I want everybody to feel well educated on this topic. It is something that I am learning more and more about myself and I'm guiding clients through using it themselves as well. And I'm pretty excited to share about my experience. So I've been on Tirzepatide for about two weeks now. I just did my third dose the other day and it has been pretty cool to see some of the changes and how calm I felt after my son had the total meltdown for, I don't know, it was at least 10 minutes. And I felt so calm, not stressed. My heart wasn't racing, my body didn't feel tight or tense. [00:22:51] It was wild. Like just how calm I felt in that moment. And I was like, whoa, Is this what everybody feels like? This is amazing. [00:23:01] I'm already seeing these hormonal changes that nothing else has been able to touch, nothing else supplement wise has been able to address. [00:23:10] I've done a lot of work around that and I would say I've already implemented a fairly insulin sensitive lifestyle. [00:23:17] But I still have most likely an undiagnosed autoimmune condition. And as I look at internal things happening again, not everything is going to happen right away, but this is what we're looking for. It's not just weight loss, but real internal healing, repair, restoration, getting your body to function the way that it's supposed to. And in order to do that we need the GLP1 receptor activation, we need the agonist to be able to bind properly to the right parts the body. And with that you are going to see amazing results. [00:23:52] So I'm really excited to share more about my experience as well as a few other case studies with you because I know it can feel intimidating. There's a lot of bad publicity, there's also a lot of misinformation and quite frankly a lot of people doing it wrong. There are a lot of people and in my opinion a lot of doctors that are just doing this wrong. We would never crank somebody on a hormone and expect good results. And yet that's what we have been doing with these peptides. And I think it's just completely backwards, it is not appropriate. And this is why so many people are struggling not just on the peptide but when they come off it. There's a better way to peptide. [00:24:30] That's what I'm here to promote and to advocate for. And this I believe is that missing metabolic piece that actually heals and repairs when we have that metabolic healing, that metabolic repair. Now the systems are in place for your body to release the weight, but we can't release the weight with broken bridges. So we've got to fix the bridge first. [00:24:51] So if you'd like to learn more about what it would look like to work with me, whether you want to use peptides or supplements or you're just looking for some coaching and support around weight loss and emotional eating and binge eating habits, I would love to chat more. You can schedule a free [email protected] schedule get on my calendar and let's talk through what has been going on for you. Where are you now, where you want to be moving forward? And I'm happy to make recommendations for you as to what I think the process and the protocol would look like. But for most People, these peptides are going to be very, very effective and we want to use them in stages like that. So think about it as six to 12 months to lose the weight. [00:25:32] Six months of maintaining and then six months most likely coming off. And it really just depends on how much weight you have to lose. But when you give yourself, what we feel like is a long amount of time. But now we are allowing our bodies to release one pound a week to where it's steady. We're maintaining lean muscle mass, we're still eating and properly fueling our bodies and we're actually repairing and restoring the internal damage because of trauma and binge eating and chronic dieting. Now we are going to see such amazing long term lasting results. [00:26:07] And there are gonna be some people that may wanna stay on peptides long term, especially if there is an autoimmune condition. But you also don't have to in order to maintain your weight loss results. That's the other piece here. Because of the healing benefits of it, your body now is functioning better and you have had time to implement the habits and make them lasting. So it's like when the habits last, your weight loss can last through the rest of your life. [00:26:32] But this is what we want to be focused on. Oh actually I remembered the thing that I was going to say earlier was around liver transplant patients and people who were on the transplant list but who were getting ready for a transplant immediately. Like those who were on the list but waiting for a transplant, they were given GLP1 agonists and it helped their current liver to function better. And so it helped them to last until the time when they could get a transplant. And so we're seeing such amazing regenerative restorative properties of these GLP one that go way beyond just weight loss. And so this is how I really want to look at it. When we have this full mind, body, emotional connection and health and restoration, this is what it's all about. I want to help people do peptides better. I want to help people selling supplements. Do your supplement business better. And let's play together. [00:27:24] This is where peptides and supplements, they can play together, but it's going to take a different approach and a different mindset. Okay, I'm done. [00:27:34] I hope you'll have a fabulous week. Here's to creating the life and body you crave. [00:27:43] If this episode resonated with you, it's time to break free from destructive cycles around food, alcohol and toxic relationships. [00:27:51] Your next step, book your free break the cycle call where you'll finally see why your binge eating and relationship patterns are so deeply connected and how to break free from both for good. [00:28:03] You'll walk away with fierce clarity and a game plan to step into a life full of fun, adventure and self love. Grab your spot now at www.bodyucrave.com BTC. [00:28:18] It's time to break the cycle. I'll show you how.

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